Real Madrid: Eden Hazard will miss the fixture with a foot injury, while Marcelo, James Rodriguez, Marco Asensio and Lucas Vazquez have also all been ruled out.
Barcelona: Ousmane Dembele remains absent for Barcelona, while Arthur is also struggling with injury after snowboarding sessions slowed his recovery. Nelson Semedo is available after returning from injury last weekend.
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Barcelona Starting XI: Ter Stegen; Semedo, Pique, Lenglet, Jordi Alba; Rakitic, Sergi Roberto, de Jong; Messi, Suarez, Griezmann.
Real Madrid Starting XI: Courtois; Carvajal, Varane, Ramos, Mendy; Valverde, Casemiro, Kroos; Bale, Benzema, Isco.